Moreover, the question of how long would it then take to develop the actual game, supposing StudioMDHR has decided on the details behind ' Cuphead 2.' The original game itself saw an extensive development time owing to various factors, winding up with Cuphead taking 5 years to complete for release. As the studio has admitted, its ideas were all included in The Delicious Last Course, meaning there may not be much elsewhere to go. Acknowledging the limited capacity StudioMDHR might have - though an argument could be made for the dev's expansion given its credibility and track record - other issues the company would need to face is how could the overall design of Cuphead be improved and expanded to justify a new game.
On the assumption that StudioMDHR does plan to release a follow-up sequel to Cuphead eventually, it's already clear that the developer has some significant challenges to overcome.